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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
G6PD
All Species:
40
Human Site:
S189
Identified Species:
62.86
UniProt:
P11413
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11413
NP_000393.4
515
59257
S189
R
L
S
N
H
I
S
S
L
F
R
E
D
Q
I
Chimpanzee
Pan troglodytes
XP_001146640
398
44780
R150
D
D
A
A
S
Y
Q
R
L
N
S
H
M
N
A
Rhesus Macaque
Macaca mulatta
XP_001095273
515
59249
S189
R
L
S
N
H
I
S
S
L
F
R
E
D
Q
I
Dog
Lupus familis
XP_538209
545
62703
S219
R
L
S
N
H
I
S
S
L
F
R
E
D
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
Q00612
515
59244
S189
Q
L
S
N
H
I
S
S
L
F
R
E
D
Q
I
Rat
Rattus norvegicus
P05370
515
59357
S189
Q
L
S
N
H
I
S
S
L
F
R
E
D
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505636
515
59203
S189
K
L
S
N
H
I
A
S
L
F
Q
E
D
Q
I
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080019
518
59674
S192
R
L
S
E
H
I
S
S
L
Y
K
E
N
Q
I
Zebra Danio
Brachydanio rerio
XP_699168
523
59677
S197
E
L
S
S
H
L
S
S
L
F
T
E
E
Q
I
Tiger Blowfish
Takifugu rubipres
P54996
530
60451
S204
E
L
S
T
H
L
S
S
L
F
T
E
D
Q
I
Fruit Fly
Dros. melanogaster
P12646
524
60412
G193
A
L
S
D
H
L
A
G
L
F
Q
E
D
Q
L
Honey Bee
Apis mellifera
XP_001121185
518
60246
S194
I
L
S
D
H
L
A
S
L
F
R
E
D
Q
I
Nematode Worm
Caenorhab. elegans
Q27464
522
60197
K195
E
L
S
T
H
L
A
K
L
F
K
E
D
Q
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJI5
515
59098
E200
Q
L
S
S
Q
I
G
E
L
F
D
E
S
Q
I
Baker's Yeast
Sacchar. cerevisiae
P11412
505
57503
Y188
E
L
Y
R
I
D
H
Y
L
G
K
E
L
V
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.9
99
87.8
N.A.
93.7
93.7
N.A.
90.2
N.A.
77.2
75.3
74.3
61.2
63.7
58.8
N.A.
Protein Similarity:
100
69.1
99.6
91.5
N.A.
97
96.6
N.A.
96.1
N.A.
89.7
85.8
82.6
74
76.8
74.9
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
93.3
93.3
N.A.
80
N.A.
73.3
66.6
73.3
53.3
73.3
60
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
100
N.A.
93.3
86.6
80
86.6
93.3
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
52.2
46.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
68.5
63.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
7
0
0
27
0
0
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
14
0
7
0
0
0
0
7
0
67
0
0
% D
% Glu:
27
0
0
7
0
0
0
7
0
0
0
94
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
80
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
7
7
0
7
0
0
0
0
0
% G
% His:
0
0
0
0
80
0
7
0
0
0
0
7
0
0
0
% H
% Ile:
7
0
0
0
7
54
0
0
0
0
0
0
0
0
80
% I
% Lys:
7
0
0
0
0
0
0
7
0
0
20
0
0
0
7
% K
% Leu:
0
94
0
0
0
34
0
0
100
0
0
0
7
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
40
0
0
0
0
0
7
0
0
7
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
20
0
0
0
7
0
7
0
0
0
14
0
0
87
0
% Q
% Arg:
27
0
0
7
0
0
0
7
0
0
40
0
0
0
0
% R
% Ser:
0
0
87
14
7
0
54
67
0
0
7
0
7
0
0
% S
% Thr:
0
0
0
14
0
0
0
0
0
0
14
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
7
0
7
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _